Sarm Powders SR9011
Product Name:SR9011
CAS NO.:1379686-29-9
Molecular Formula:C23H31ClN4O3S
Molecular Weight:479.03524
Purity:99%
Appearance:White Powder
Grade:Pharmaceutical Grade
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV ERB α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice.
The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.
Sarm Powders Stenabolic SR9009
Product Name:SR9009
CAS NO.:1379686-30-2
Molecular Formula:C20H24ClN3O4S
Molecular Weight:437.94026
Purity:99%
Appearance:White Powder
Grade:Pharmaceutical Grade
In spite of being associated with SARMS, Stenabolic (SR9009) is in fact a Rev-ErbA ligand. It means SR binds to this protein and makes it more active. As a result, the user will experience a lot of positive effects, such as increased fat loss, enhanced endurance, and many other health benefits.
As mentioned beforehand, SR9009 is a synthetic Rev-Erb ligand, which is taken orally. This is a very unique compound. By stimulating the Rev-Erb protein, SR9009 has the ability to greatly influence a lot of regulatory mechanisms in the human body. For instance, it can affect the circadian rhythms, lipid and glucose metabolism, fat-storing cells, as well as macrophages. Hence, Stenabolic will allow the user to lose fat and drastically increase endurance, both of which are very desirable effects for an athlete.
Uses in bodybuilding
There is no need to be a genius to realize all the possibilities SR9009 opens to an athlete - amazing endurance and strength, fat loss, muscle hypertrophy (growth), improved cholesterol and blood sugar levels, and an increased metabolism. Hence, one can expect results similar to those seen with Cardarine (GW-501516), but with considerably more extra benefits. Besides, since stenabolic works great both solo or stacked, it will be a very good addition to any steroid or SARMS cycle, and it will give especially impressive results when used together with Cardarine.
All in all, Stenabolic will allow you to do more cardio training, lift more, lose fat, gain lean muscle mass, and improve cholesterol levels. Cholesterol and cardio management is very important when using SR in combination with such steroids as Anavar or Trenbolone.
Medical uses
Logically, with so many positive effects, SR9009 will have an extremely varied use in medicine. For instance, the drastic decrease in triglycerides and plasma glucose will be a huge help in the treatment of type 2 diabetes. What’s more, Stenabolic will be a crucial element in the treatment of sarcopenia - muscle and strength loss caused by aging.
Additionally, SR9009 will allow doctors to treat obesity in those who for medical reasons cannot train or carry out any exercises, as it can replace exercise. Finally, it is very hard to overestimate its effectiveness in the treatment of cholesterol related conditions or metabolic syndromes.
Recommended dosages
The optimal dosages range from 20 to 30 milligrams (mgs) per day. However, there is one drawback - due to a very short half life, you will need to space it out throughout the day for the best balance of the active substance in the body. Thus, it is best to use stenabolic every 2-4 hours, depending on the exact dosage used. For example, when the daily dosage is 30 mgs, you can take 10 mgs every 4 hours.
